CRP (C-reactive protein) is a general marker of inflammation that can rise during menopause due to hormonal shifts. However, it is not specific to menopausal symptoms like hot flashes or mood changes. Evidence links elevated CRP in menopause more to cardiovascular risk than to typical menopause complaints. While CRP measurement can be part of a broader health assessment, it should not replace specific hormone testing (estradiol, FSH) for diagnosing menopause. The evidence is moderate: CRP is well-validated for inflammation but not for menopause-specific guidance. Lifestyle factors (diet, exercise, smoking) strongly influence CRP levels. Therefore, CRP is useful as a supplementary marker but not as a standalone tool for menopause management.
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