Can Progesteron help with Langlebigkeit?

Whether progesterone can promote longevity is not scientifically established. Progesterone is a key steroid hormone involved in the menstrual cycle and pregnancy. Preclinical studies suggest it may have neuroprotective and anti-inflammatory effects that could theoretically slow aging. However, robust long-term human trials directly linking progesterone supplementation to increased lifespan are lacking. Hormone replacement therapy (HRT) with progesterone can relieve menopausal symptoms like hot flashes, but it also carries risks (e.g., thrombosis, breast cancer). In men, the effects of progesterone on longevity are even less studied. Home hormone tests (e.g., from MyBody-X) can measure progesterone levels, but a single measurement is unreliable due to circadian and cycle-related fluctuations. Without medical supervision and individual risk assessment, supplementation is not advisable. Evidence: mechanistic (preclinical), but no strong human evidence for longevity.