What to watch with Folsäure and skin aging?

Folic acid (vitamin B9) is often discussed in relation to skin aging due to its role in DNA repair and cell turnover. Some evidence suggests adequate folate may protect against UV-induced damage and support collagen synthesis, potentially slowing skin aging. However, the evidence is limited: most comes from in vitro or animal studies, not robust human trials. Additionally, high-dose folic acid supplementation can mask vitamin B12 deficiency, which is especially risky for older adults and vegetarians. There is also concern that excess folic acid might promote the growth of pre-existing cancer cells. For skin aging specifically, deficiency may contribute to premature aging, but supplementation beyond dietary intake is not generally recommended. Watch for interactions with medications like methotrexate. The best approach is a balanced diet rich in natural folates (leafy greens, legumes) and to check your B12 and folate levels before taking high-dose supplements. Evidence is moderate overall.