warum nehme ich nicht ab — which blood markers matter?

The question 'why am I not losing weight' is complex and cannot be reduced to a single blood marker. From an evidence-based perspective, several lab values can indicate metabolic obstacles. Fasting insulin, glucose, and HbA1c are key – elevated levels suggest insulin resistance, which impairs fat oxidation. Thyroid markers (TSH, fT3, fT4) are critical because hypothyroidism lowers basal metabolic rate. Inflammatory markers like hsCRP may reflect chronic low-grade inflammation linked to weight loss resistance. Vitamin D, B12, and iron status affect energy metabolism. MyBody-X blood tests (e.g., Cardio Risk Check) measure cholesterol, LDL, HDL, triglycerides, and hsCRP – these are primarily for cardiovascular risk, not directly validated for weight loss. Genetic tests (e.g., ADRB3 variant) have only weak, mechanistic evidence for fat metabolism. Importantly, no single marker explains weight loss failure; clinical interpretation by a physician is essential. Evidence ranges from human-observational (insulin, glucose) to mechanistic (vitamins).