Preparation for a hair loss test depends on the specific kit. For DNA-based tests (e.g., analyzing AR, SRY, or other SNPs), typical instructions include: no eating, drinking, or smoking for 30 minutes before saliva collection. For blood-based biomarker tests (e.g., ferritin, vitamin D, thyroid panel), fasting may be required. Avoid biotin supplements for at least 3 days before blood sampling, as biotin can interfere with immunoassays. However, the evidence for most direct-to-consumer hair loss tests is weak to mixed. Genetic variants associated with androgenetic alopecia have small effect sizes and are not clinically actionable on their own. A dermatologist or trichologist can provide a more comprehensive evaluation including scalp examination, blood work, and possibly a biopsy. Do not change your hair care routine or start treatments solely based on a home test result. Evidence grade: mixed (some GWAS associations exist, but predictive value is low; marketing often overstates).
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