CRP (C-reactive protein) is a non-specific marker of inflammation. Chronically elevated CRP levels may indicate systemic inflammation, which has been associated with fertility issues such as endometriosis, PCOS, and implantation failure. In men, inflammation can also impair sperm quality. However, CRP is not a direct cause but rather a correlate. Evidence comes mostly from observational studies; causal links are not firmly established. A single CRP test is insufficient for fertility diagnosis. A comprehensive workup by specialists—including other inflammatory markers, hormones, and lifestyle factors—is recommended. Elevated CRP in recurrent pregnancy loss or unexplained infertility may point to underlying inflammation but must be interpreted clinically. MyBody-X DNA tests do not directly cover CRP genetics; the associations mentioned are based on general medical literature.
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