Myths vs facts: HLA-DQ2 and Schlaf

The question about myths vs facts regarding HLA-DQ2 and sleep cannot be directly answered from the provided context. HLA-DQ2 is a well-established genetic risk factor for celiac disease, an autoimmune condition triggered by gluten. Untreated celiac disease can impair sleep through chronic inflammation, nutrient deficiencies (e.g., iron, vitamin D), or comorbid conditions like fatigue and restless legs. A common myth is that HLA-DQ2 alone—without celiac or gluten sensitivity—directly causes sleep disturbances. There is no strong evidence for this. HLA-DQ2 is an immune gene, not a sleep gene. The link to sleep is indirect and only plausible in the context of active celiac or non-celiac gluten sensitivity. The provided context contains no studies or data on this specific topic. Evidence is therefore rated as 'mechanistic/unclear'. Consumers should understand that a positive HLA-DQ2 test without a celiac diagnosis does not warrant sleep-related dietary changes. For sleep issues, other factors (stress, sleep hygiene, medical causes) are more likely.