What to watch with Leaky Gut Test and gut health?

The Leaky Gut Test (e.g., measuring zonulin) is a controversial marker for intestinal permeability. Evidence for its clinical utility is limited – it is not a standard diagnostic tool. Instead, focus on a fiber-rich diet, fermented foods, adequate vitamin D (VDR gene is relevant), and omega-3 fatty acids (anti-inflammatory). Stress management and sleep are also crucial. A DNA test for ADIPOQ or VDR may offer clues but does not replace lifestyle changes. For persistent symptoms (bloating, diarrhea), consult a doctor. The test alone says little about overall gut health – combine it with a symptom diary and possibly a stool analysis. Evidence: mixed – mechanistically plausible but not sufficiently validated clinically.