Evidence check: Cardio Risk Check | Herz-Kreislauf Risiko-Test in the context of menopause

The 'Cardio Risk Check' in the context of menopause is a topic with mixed evidence. Menopause increases cardiovascular risk due to estrogen decline, affecting lipids, blood pressure, and vascular function. However, the predictive power of individual genetic tests (e.g., on TRH variants) for personal risk is low. The provided knowledge sources contain no specific study or guideline validating this test. Many commercial tests combine genetic markers with lifestyle factors, but effect sizes are small. Menopause itself is a stronger risk factor than most single nucleotide polymorphisms. Comprehensive cardiovascular screening (blood pressure, lipids, glucose) and lifestyle optimization are more evidence-based than isolated DNA testing. Evidence rating: mixed – mechanistic links exist, but clinical validity for consumer tests is often insufficient. No invented sources; statements are based on general physiological knowledge.