When monitoring insulin and blood sugar, key metrics include fasting glucose, HbA1c, postprandial glucose, and fasting insulin (to calculate HOMA-IR for insulin resistance). Genetic variants like TCF7L2 are sometimes marketed for carb sensitivity, but effect sizes are small and evidence is weak (marketing/unclear). The BDNF Val66Met variant has shown moderate association with metabolic markers in type 2 diabetes in one cross-sectional study, but not sufficient for personalized dietary advice. More evidence-based approaches include continuous glucose monitoring (CGM) and food logging. Be cautious with drug interactions (e.g., metformin, insulin) and avoid extreme diets without medical supervision. Caveat: consumer DNA tests often report weak associations, not clinical diagnoses. Focus on lifestyle factors: diet quality, physical activity, sleep, and stress management.
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