Ferritin is a storage protein for iron and a key biomarker of iron status. Balanced iron levels are relevant for fertility, as both deficiency and overload can impair reproductive function. Observational studies suggest that iron deficiency may be linked to ovulatory infertility, and iron supplementation in deficient women might improve fertility outcomes. However, the evidence is moderate: no large randomized controlled trials directly prove a causal effect of ferritin on fertility. Genetic variants (e.g., in HFE) can influence iron metabolism, but a consumer DNA test for ferritin and fertility is not clinically established. A blood ferritin test is more informative than a genetic test. Caution: iron overload (hemochromatosis) can also harm fertility. Supplementation should only be considered after confirmed deficiency.
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