Evidence check: hsCRP in the context of menopause

hsCRP (high-sensitivity C-reactive protein) is an inflammatory marker that can rise during menopause due to hormonal shifts, particularly estrogen decline. Evidence suggests a moderate association between elevated hsCRP and increased cardiovascular risk in postmenopausal women. However, hsCRP is non-specific—elevations can stem from infections, smoking, or obesity. Its utility for individual menopause management is limited; it should be interpreted alongside traditional risk factors. Consumer tests may overstate its predictive value. Evidence: human-moderate. Caveat: hsCRP alone does not diagnose menopause-related conditions; clinical context and additional biomarkers are needed.