Magen-Darm-Gesundheit: can a DNA test help?

DNA tests can offer limited help for gut health by analyzing genes like LCT (lactose intolerance) or HLA-DQ (celiac risk). Evidence is moderate: LCT variants do not mean complete intolerance, and HLA-DQ markers are risk factors, not diagnostic. For general digestive issues or food sensitivities, DNA tests are insufficient. IgG food panels are not recommended by guidelines—they reflect exposure, not intolerance. Microbiome tests provide a snapshot but lack proven actionable guidance. In summary, DNA tests can address specific genetic predispositions but do not replace clinical evaluation. Evidence is mixed: human-moderate for some genes, but weak or marketing-driven for most claims.