Myths vs facts: Folsäure and Abnehmen

Folic acid (vitamin B9) is often marketed as a weight-loss aid, but the scientific evidence is weak and inconsistent. Some observational studies suggest an inverse association between folate status and body weight or metabolic syndrome, yet randomized controlled trials do not confirm a causal effect of folic acid supplementation on weight loss. Mechanistically, folate may influence homocysteine metabolism and methylation pathways involved in fat oxidation, but any effect is small and clinically insignificant. Moreover, high-dose folic acid can mask vitamin B12 deficiency, a risk especially for older adults and vegans. The claim that folic acid alone leads to meaningful weight loss is a myth. A diet rich in natural folate sources (leafy greens, legumes) supports overall health but should not be promoted as a weight-loss solution. Evidence grade: mixed – mechanistic plausibility exists, but human trial data are lacking.