When is IgG Unverträglichkeit Genetik actually useful?

The question of when IgG food intolerance testing (often mislabeled as 'genetics') is useful requires clear differentiation: IgG antibody tests measure immune responses to foods, but they are not genetic tests. Evidence for their clinical utility in food intolerance is weak. Major medical societies, including the European Academy of Allergy and Clinical Immunology (EAACI), advise against IgG-based tests because they frequently yield false positives and do not correlate with true intolerance. Genetic tests, on the other hand, can be useful for specific genetically determined intolerances such as lactose intolerance (LCT gene) or celiac disease (HLA-DQ2/DQ8), which have strong evidence. For most other food intolerances (e.g., histamine intolerance), the genetic component is weak or unclear. An IgG test provides no useful genetic information and should not be used to guide elimination diets. A sensible approach involves medical evaluation with validated methods (e.g., breath test for lactose, biopsy for celiac). The evidence for IgG testing is largely marketing-driven.