was kostet ein gentest erbkrankheiten — can a DNA test help?
T
TIKKI knowledge answer
The cost of a genetic test for hereditary diseases varies widely: direct-to-consumer (DTC) tests like 23andMe or MyHeritage typically range from €100–300, but they usually screen only for selected risk variants, not full gene analysis. Clinical tests for monogenic disorders (e.g., cystic fibrosis, Huntington's disease) are more expensive (€500–3000) and require a physician's order. A DNA test can help if it targets well-established mutations with high penetrance and results are interpreted through genetic counseling. However, many hereditary diseases are polygenic or multifactorial, so a positive finding indicates risk, not diagnosis. Evidence for DTC tests is often weak ('practice'), whereas clinical tests rely on strong human data. Important: a genetic test does not replace medical examination. Misinterpretation can lead to unnecessary anxiety or false reassurance. For serious family history, seek genetic counseling before testing.
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