Magnesium is an essential mineral involved in over 300 enzymatic reactions, including those relevant to fertility. In women, magnesium supports hormone regulation (LH, FSH), egg maturation, and implantation. Deficiency has been linked to ovarian dysfunction, PMS, and increased miscarriage risk. In men, magnesium contributes to sperm quality by improving motility and reducing oxidative stress. However, the evidence is mostly mechanistic and observational; robust RCTs are limited. Supplementation may be beneficial if deficiency is confirmed, but excess intake can cause diarrhea and cardiac issues. The tolerable upper intake level from supplements is 250 mg/day (EFSA). Magnesium plays a supportive but not standalone role in fertility.
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