Can HLA-DQ2 help with weight loss?

HLA-DQ2 is strongly associated with celiac disease, not weight loss. There is no credible scientific evidence that HLA-DQ2 directly aids weight loss. In celiac disease, a gluten-free diet may lead to weight normalization, but this is a secondary effect of treating the condition, not a weight-loss property of the gene itself. For individuals without celiac disease, HLA-DQ2 has no proven relevance to weight management. Weight loss is multifactorial (caloric balance, physical activity, metabolism). Claims that HLA-DQ2 can help with weight loss are misleading and unsupported by evidence. Caveat: consumer genetic tests often oversimplify; HLA-DQ2 should only be interpreted in the context of celiac disease diagnosis.