Can Cortisol help with Langlebigkeit?

Cortisol is an essential hormone that helps manage acute stress, but chronically elevated levels are consistently linked to accelerated aging—shorter telomeres, impaired immunity, and metabolic dysfunction. The notion that supplementing cortisol could promote longevity is not supported by evidence. In fact, exogenous cortisol (e.g., glucocorticoids) causes Cushing's syndrome, muscle wasting, osteoporosis, and insulin resistance. Some research explores cortisol modulation through lifestyle interventions (stress reduction, sleep, exercise) as part of a longevity strategy, but direct supplementation is contraindicated. The evidence is mechanistic/unclear. Caveat: no human longevity trials exist; risks outweigh any hypothetical benefits.