Is CYP2D6 useful for Abnehmen?

CYP2D6 is a drug-metabolizing enzyme, not a weight-loss gene. There is no strong evidence that CYP2D6 variants predict or improve weight loss outcomes. Some direct-to-consumer tests claim links to metabolism or appetite, but randomized trials (e.g., PMID 37813841) show no benefit of genotype-matched diets for weight loss. Single-gene effects are small; overall diet quality, calorie balance, and physical activity matter far more. Additionally, using CYP2D6 results without medical supervision can lead to misinterpretation or risky self-medication. Bottom line: CYP2D6 is not useful for weight loss – focus on evidence-based lifestyle changes instead.