Typical symptoms of elevated cortisol include weight gain (especially abdominal), fatigue, sleep disturbances, irritability, anxiety, high blood pressure, weakened immune function, and difficulty concentrating. These symptoms are non-specific and can stem from many causes. Chronic high cortisol (e.g., from prolonged stress) may lead to metabolic and cardiovascular issues over time. MyBody-X offers tests analyzing genes like CLOCK and MAOA, which have been linked to stress regulation. However, the evidence that these genes can reliably predict cortisol levels or lifespan is weak and not clinically validated. Such tests are more marketing than science and cannot replace medical evaluation. If you suspect a cortisol imbalance, consult a doctor for proper testing (e.g., salivary or blood cortisol). Consumer DNA tests do not provide actionable clinical insights for cortisol management.
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