What role does CRP Entzündung play in Wechseljahre?

CRP (C-reactive protein) is a non-specific inflammatory marker produced by the liver. During menopause, estrogen decline is associated with a mild increase in systemic inflammation. Observational studies indicate that postmenopausal women tend to have higher CRP levels than premenopausal women, partly due to the loss of estrogen's anti-inflammatory effects. However, CRP is not a specific marker for menopause; elevated levels can also result from obesity, metabolic syndrome, or other inflammatory conditions. The clinical relevance is limited: moderately elevated CRP in menopause is more a correlate than a causal risk factor. Consumer DNA tests offering CRP-related genetic or inflammation scores lack validated predictive power for menopausal symptoms. Evidence is based on observational studies, not RCTs. Lifestyle interventions—exercise, Mediterranean diet, stress reduction—can lower CRP, but direct supplementation or genetic testing is not recommended. Be cautious of marketing that frames CRP as a 'key hormone' of menopause.