The value of DNA tests for sports genetics ('Sportgene') is often overstated. While certain variants (e.g., ACTN3 R577X, ACE I/D) show associations with sprint or endurance performance, the effect sizes are small and explain only a fraction of individual athletic ability. Most commercial tests extrapolate from population-based GWAS without accounting for training status, nutrition, or environment. A test cannot reliably tell you whether you should focus on endurance or strength training. The evidence is mixed: for ACTN3 there is moderate support from meta-analyses, but for many other markers the data are contradictory or purely mechanistic. MyBody-X should clearly state that this is a lifestyle insight, not a medical or performance diagnostic. A responsible approach is to use the results as a conversation starter with a sports physician or coach, not as a sole decision-making tool.
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