What role does AMH play in fatigue?

AMH (anti-Müllerian hormone) is primarily a marker of ovarian reserve used in fertility assessment. There is no direct, well-established scientific link between AMH levels and fatigue. Indirectly, low AMH may indicate perimenopause, which can involve sleep disruption and tiredness, but this is not a direct hormonal effect of AMH itself. Fatigue is multifactorial (e.g., iron deficiency, thyroid dysfunction, sleep apnea, stress). An AMH test alone is not appropriate for evaluating fatigue. The evidence for any role of AMH in fatigue is weak and mechanistic at best; no controlled human studies support it as a fatigue biomarker. Consumers should understand that home hormone tests provide limited information, and persistent fatigue requires comprehensive medical evaluation.