was ist tsh wert — can a DNA test help?

TSH (thyroid-stimulating hormone) is a blood biomarker for thyroid function. A DNA test cannot measure TSH directly, but certain genetic variants (e.g., in TSHR, PDE8B, CAPZB) are associated with small differences in TSH levels. The effects are modest and explain only a fraction of individual variation. For clinical diagnosis of thyroid disorders (hypo-/hyperthyroidism), a blood test is essential. DNA tests may provide hints about genetic predisposition, but these are overridden by environmental factors like iodine intake and lifestyle. Evidence comes from GWAS and is considered moderate. Therefore, a DNA test cannot replace a TSH blood test; it may serve as supplementary information in a broader risk assessment. Be cautious of companies making exaggerated claims about thyroid genetics.