The question of whether FTO (fat mass and obesity-associated gene) is useful for allergies cannot be clearly answered with current evidence. FTO is primarily known for its strong association with body weight, appetite regulation, and obesity risk – not directly with allergic diseases. Some studies have explored weak links between FTO variants and asthma or atopic conditions, but results are inconsistent and often mediated by BMI. The provided context does not mention FTO; there is only a reference to food allergies and ARFID (PMC13029006), which does not involve FTO. For allergies, relevant genes include HLA, FLG (filaggrin), and IL-33. Therefore, FTO testing is not useful for allergy prediction or management. Evidence grade: unclear. Consumers should rely on established clinical and genetic markers rather than FTO scores for allergy-related decisions.
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