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Evidence check: FUT2 in the context of Blutzucker

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Evidence check: FUT2 in the context of Blutzucker

FUT2 (fucosyltransferase 2) determines secretor status – whether blood group antigens are secreted into body fluids. In the context of blood sugar, GWAS have linked certain FUT2 variants (e.g., rs601338) to modest increases in fasting glucose. The effect is small and likely mediated through gut microbiome composition and vitamin B12 levels. Non-secretors (GG genotype) tend to have a less favorable microbiome and lower B12, which may indirectly impair glucose regulation. Evidence is primarily genetic-associative (GWAS) and mechanistic, not sufficient for clinical recommendations. Direct causal impact on blood glucose is not established. MyBody-X tests including FUT2 should be seen as supplementary information, not a diagnostic tool or sole basis for dietary changes. Safety note: persistent blood sugar issues require medical evaluation.

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