Is CYP1A2 useful for Sport?

CYP1A2 is a key enzyme for caffeine metabolism. The rs762551 variant (CYP1A2*1F) classifies individuals as slow or fast metabolizers. In sports, caffeine is commonly used as an ergogenic aid. Some studies suggest fast metabolizers benefit more from caffeine (e.g., for endurance performance), while slow metabolizers may experience less benefit or even adverse effects like increased heart rate or anxiety. However, the evidence is not strong enough for personalized recommendations. Many other factors (training, diet, other genetics) play a role. Consumer tests may report this variant, but the clinical utility for sport is limited. The provided context contains no specific information on CYP1A2, so this answer is based on general scientific knowledge. Caution: no direct evidence from the context.