The utility of sports genetic testing (Sportgene Genetik) is limited and context-dependent. While certain gene variants like ACTN3 R577X and ACE I/D have been associated with power vs. endurance performance, effect sizes are small and not deterministic. Official sports medicine guidelines do not recommend routine genetic testing for talent identification or training personalization due to insufficient evidence from large-scale randomized trials. Most evidence comes from observational studies or GWAS, with few replication studies in diverse populations. A DNA test might be useful for identifying rare monogenic conditions (e.g., malignant hyperthermia) or for understanding caffeine metabolism (CYP1A2) or injury risk (COL5A1), but these applications require clinical interpretation. For the average consumer, the predictive value is low, and lifestyle factors dominate. Therefore, sports genetics is most useful when combined with professional coaching and as part of a broader assessment, not as a standalone tool. Marketing claims often overstate benefits. Evidence grade: mixed/unclear.
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