What role does Zöliakie Test play in weight loss?

A celiac test (e.g., HLA-DQ2/DQ8 genotyping or tissue transglutaminase antibodies) does not directly cause weight loss. Its indirect role is to identify undiagnosed celiac disease, which can lead to unintended weight loss due to malabsorption or, paradoxically, weight gain from inflammation and cravings. However, most overweight individuals do not have celiac disease. A positive genetic marker alone does not confirm active disease; serology and biopsy are required. Consumer DNA tests often provide only risk indications, not a diagnosis. For weight loss, relying on a celiac test is misguided; the foundation remains balanced nutrition and calorie control. Evidence for weight loss from a gluten-free diet in healthy people is weak. Conclusion: The test may be medically relevant in specific cases but is not a weight-loss tool.