Myths vs facts: Progesteron and Darmgesundheit

The claim that progesterone directly impacts gut health is partially true but often overstated. Progesterone can slow gut motility, leading to constipation – a common symptom in pregnancy or hormone replacement therapy. Human studies suggest progesterone may influence microbiome composition, but data are limited and not conclusive. Many 'gut health myths' on social media assert that progesterone deficiency automatically causes leaky gut or dysbiosis – robust clinical evidence for this is lacking. The provided context contains no specific studies on progesterone and gut health. Therefore, caution is warranted: anecdotal reports or animal studies cannot be directly extrapolated to humans. Anyone taking progesterone supplements and experiencing digestive issues should consult a physician rather than rely on self-tests. Evidence: human-moderate (for motility effects), but for microbiome changes it is more mechanistic or unclear.