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Myths vs facts: IgG and blood sugar

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Myths vs facts: IgG and blood sugar

Whether a pharmacogenetic (PGx) test like MyBody-X is useful when starting an SSRI for your teenage daughter requires a nuanced answer. Yes, such tests can detect variants in CYP2D6 and CYP2C19 that influence SSRI metabolism. The evidence is human-strong, based on reviews (e.g., PMC13124575, PMC13222629). However, clinical predictive power is limited: the test indicates genetic risk for altered metabolism, not actual efficacy or side effects. Many other factors (age, liver function, drug interactions) are equally important. A PGx test can serve as additional information but should never replace medical supervision. For your daughter, it is especially critical to adjust medication only under a doctor's guidance. The test alone does not prevent side effects – it only provides a clue. Discuss results with a child and adolescent psychiatrist. Evidence: human-strong. Sources: PMC13124575; PMC13222629.

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