Evidence check: CRP Entzündung in the context of weight loss

CRP (C-reactive protein) is a well-established inflammation marker. Strong human evidence (meta-analyses, RCTs) shows that moderate weight loss of 5–10 % in overweight or obese individuals significantly lowers CRP, primarily by reducing visceral fat which secretes pro-inflammatory cytokines. A blood CRP test can serve as a monitoring parameter, but it is not a direct weight management tool. Caution: single measurements are non-specific; acute infections or chronic diseases can elevate CRP. Consumer DNA tests for CRP variants (e.g., rs1205) have small effect sizes and are not clinically actionable. Conclusion: Measuring CRP during weight loss is reasonable, but not as a sole success indicator. The most effective interventions remain calorie restriction and regular exercise.