The provided context does not contain direct information on the role of glucose in fatigue. Generally, glucose is the primary energy source for the brain and muscles. A drop in blood glucose (hypoglycemia) can cause fatigue, poor concentration, and lethargy. However, the effect is context-dependent: in healthy individuals with normal metabolism, balanced carbohydrate intake provides stable energy, while large blood glucose swings – e.g., after high-sugar meals – can trigger reactive hypoglycemia and subsequent fatigue. Chronically elevated glucose (as in diabetes) is also associated with fatigue. The evidence is based on basic physiology and clinical observation, not on the provided articles. Therefore, the strength is limited; individual factors like insulin sensitivity, physical activity, and diet are crucial.
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