Is Folsäure useful for Abnehmen?

The question of whether folic acid (vitamin B9) aids weight loss cannot be answered affirmatively based on current evidence. Folic acid is crucial for cell division, DNA synthesis, and homocysteine metabolism. Some mechanistic hypotheses suggest that folate deficiency might impair fat metabolism, possibly via elevated homocysteine linked to insulin resistance. However, robust placebo-controlled intervention trials demonstrating significant weight loss from folic acid supplementation in adequately nourished individuals are lacking. Existing studies show either no or marginal effects, often in combination with other B vitamins. Moreover, folic acid is already widely available through fortified foods in many countries, making additional supplementation unlikely to provide extra benefit. High doses (>1 mg/day) can mask vitamin B12 deficiency, a safety concern especially for older adults and vegans. For evidence-based weight management, calorie deficit, balanced nutrition, and physical activity remain key. Folic acid alone is not a weight loss aid. Evidence grade: mechanistic/insufficient.