Longevity DNA Test: which blood markers matter?

A longevity DNA test does not measure blood markers; it analyzes genetic variants. Blood markers such as HbA1c, CRP, LDL/HDL, triglycerides, vitamin D, homocysteine, liver enzymes, and creatinine are more directly linked to aging processes and disease risk. Evidence for individual markers is sometimes strong (e.g., HbA1c and mortality), but a single blood value cannot predict overall lifespan. DNA tests for longevity (e.g., FOXO3) have only tiny effects and are often overhyped. Clinically, a regular blood panel with metabolic markers is more actionable. Caveat: No test – DNA or blood – can predict your individual lifespan. Evidence for blood markers in longevity research is mostly observational (human-moderate).