What to watch with VDR and Haut?

The vitamin D receptor (VDR) is crucial for skin health: it regulates cell proliferation, barrier integrity, and immune responses in the skin. A functional VDR supports wound healing, UV protection, and inflammation control. Variants like rs2228570 (FokI) or rs1544410 (BsmI) may slightly alter receptor activity, but effect sizes are small and not deterministic. MyBody-X DNA tests may include VDR, but the clinical utility is limited. More actionable are measured vitamin D levels, sun exposure, skin type, and diet. For skin conditions like psoriasis or eczema, VDR genotyping can offer clues but does not replace medical diagnosis. Caution: avoid high-dose vitamin D without blood testing, as toxicity is possible. Evidence: human-moderate.