What role does IgE Allergietest play in Wechseljahre?

The IgE allergy test measures specific antibodies to allergens and is primarily used to diagnose type I hypersensitivity reactions. During menopause (climacteric), hormonal fluctuations—particularly the decline in estrogen—can modulate immune function, which may theoretically influence allergic responses. However, there is no strong evidence that IgE testing provides direct benefit for managing menopausal symptoms or predicting allergy changes in this life stage. Some women report new or worsening allergies during perimenopause, but the data are limited to observational and mechanistic studies. Therefore, IgE testing is not a standard or recommended tool for menopause care. More relevant markers include hormone panels, thyroid function, and inflammatory markers like hs-CRP. An IgE test should only be ordered when there is a specific clinical suspicion of allergy, not as a general wellness screen. The evidence for its role in menopause is weak and largely anecdotal.