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Evidence check: Cardio Risk Check in the context of Stress

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Evidence check: Cardio Risk Check in the context of Stress

A 'Cardio Risk Check' in the context of stress often claims to assess individual cardiovascular risk by incorporating stress markers (e.g., cortisol, genetic variants). However, the evidence is weak: while chronic stress is a recognized risk factor for CVD, most commercial tests combine biomarkers or SNPs without adequate clinical validation. No prospective studies demonstrate that interventions based on such test results improve cardiovascular outcomes. Genetic components (e.g., variants in stress-axis genes) typically have small effect sizes and are not predictive. Moreover, there are no established reference ranges for 'stress' in blood or saliva that allow reliable risk stratification. Such a test may lead to false reassurance or unnecessary anxiety. Instead, focus on established risk factors (blood pressure, lipids, smoking, exercise) and stress management (sleep, mindfulness). Consult a physician for evidence-based cardiovascular risk assessment.

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