Preparing for exercise while on weight-loss injections (GLP-1 agonists like semaglutide or tirzepatide) requires caution. These drugs slow gastric emptying, which can cause nausea, fullness, and fatigue – especially early in treatment. Recommendations: 1) Start with moderate intensity (e.g., walking, light resistance training) and increase gradually. 2) Stay well-hydrated and consider electrolyte drinks, as reduced appetite may lead to dehydration. 3) Eat a small, protein-rich meal 1–2 hours before exercise (e.g., yogurt, protein shake) to minimize nausea. 4) Listen to your body – if you feel dizzy or overly nauseous, take a break. 5) Consult your doctor before starting any new exercise regimen. Evidence is based on clinical practice and observational studies; no specific RCTs exist for this combination. Important: The injection does not replace healthy diet and exercise – it supports weight loss, but muscle building and fitness require active training.
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