was sind tsh werte — which blood markers matter?

The question about TSH values and which blood markers matter cannot be directly answered from the provided context, which focuses on DNA tests and genes like APOE or FTO. Nevertheless, TSH (thyroid-stimulating hormone) is the primary screening marker for thyroid function. Normal TSH typically ranges from 0.4 to 4.0 mU/L, though reference intervals vary by laboratory and age. If abnormal, free T4 (fT4) and free T3 (fT3) are measured to diagnose hyper- or hypothyroidism. Additional antibodies (TPO-Ab, TRAb) can indicate autoimmune conditions such as Hashimoto's or Graves' disease. While genetic factors (e.g., variants in PDE8B or TSHR) can influence TSH levels, they are not covered in the given context. The evidence for these markers is based on decades of clinical practice and guidelines. Caveat: This answer does not replace medical advice; individual reference ranges and comorbidities must be considered.