What should I know about gluten unvertraglichkeit?
T
TIKKI knowledge answer
Gluten intolerance includes celiac disease (autoimmune, well-established diagnostics) and non-celiac gluten sensitivity (NCGS, no biomarkers). Genetic testing for HLA-DQ2/DQ8 can indicate increased risk for celiac disease but is not diagnostic – duodenal biopsy remains the gold standard. For NCGS, no validated genetic markers exist. The provided context lacks specific studies on gluten; the included information on CLOCK genes and microbiome tests suggests that MyBody-X often relies on marketing without clinical validation. Therefore, caution is warranted: a DNA test alone cannot confirm or rule out gluten intolerance. If celiac disease is suspected, a physician should perform antibody tests (tTG-IgA) and possibly a biopsy. For NCGS, only a controlled elimination diet helps. The evidence for genetic tests on gluten intolerance is mixed: strong for celiac risk, weak for NCGS. Without medical guidance, false conclusions may arise.
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