The risks and limits of sport genetics tests for women stem primarily from overclaimed associations. Many direct-to-consumer (DTC) tests suggest that variants in genes like MC4R or GPX1 influence athletic performance or recovery. However, evidence is weak: MC4R variants are linked to obesity, not stress response (source: deep-qa-batch-2364). GPX1 variants have small effects on antioxidant enzymes; high-dose selenium supplements can be toxic (source: deep-qa-batch-1362). VKORC1 variants only matter for warfarin dosing, not sports (source: deep-qa-batch-1309). These tests often ignore lifestyle, training, and nutrition. Clinical utility is low, and misinterpretation may lead to false reassurance or unnecessary worry. Women should view such results with caution and not base training or diet decisions solely on genetic data.
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