The question of myths vs facts regarding celiac testing and longevity requires careful analysis. A common myth is that a genetic test (HLA-DQ2/DQ8) alone can diagnose celiac disease. Fact: these genes are necessary but not sufficient – about 30 % of the population carries them, yet only 1–2 % develop celiac. A positive genetic test without antibody confirmation (tTG-IgA) and duodenal biopsy is not diagnostic. Another myth is that a positive celiac test automatically mandates a gluten-free diet for longevity. In reality, only individuals with confirmed celiac disease benefit from strict gluten avoidance; for healthy people, there is no evidence that a gluten-free diet extends lifespan. Untreated celiac can reduce life expectancy due to malabsorption and chronic inflammation, but the test alone does not predict longevity. The evidence is mixed: while diagnostic criteria are well-established, long-term studies directly linking celiac screening to increased longevity are lacking. Consumer DNA tests often overstate clinical utility. Safety note: anyone suspecting celiac should consult a physician before starting a gluten-free diet.
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