Question
Do polygenic scores derived from European cohorts accurately predict disease risk in non‑European populations?
Health · EN
Do polygenic scores derived from European cohorts accurately predict disease risk in non‑European populations?
Review status disclosedPublic · privacy gate
TIKKI knowledge answer
No. Polygenic scores (PGS) generated from European cohorts may not accurately predict disease risk in non‑European populations, reflecting reduced portability across ancestries.
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