Genes are the fundamental units of heredity, composed of DNA, that provide instructions for making proteins. They influence everything from eye color to disease risk. When should you see a doctor? If you have unexplained symptoms that might indicate a genetic condition (e.g., chronic fatigue, developmental delays, or a strong family history of certain cancers), a genetic counselor or physician can help. Also, if you take a direct-to-consumer (DTC) genetic test and receive results suggesting high risk (e.g., polygenic risk scores for heart disease or variants like MTHFR), do not make drastic changes without professional guidance. DTC tests often have limited clinical validity, especially for non-European populations, and can cause unnecessary anxiety. A doctor can interpret results in the context of your overall health, family history, and lifestyle, and recommend appropriate follow-up. Remember: genes are only one factor; environment, lifestyle, and chance also matter greatly.
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