TSH (thyroid-stimulating hormone) is a well-established marker of thyroid function. Optimal TSH levels (approximately 0.5–2.5 mU/L) are associated with better metabolic health, cardiovascular function, and cognitive performance – all factors that can contribute to longevity. However, direct evidence for TSH as an independent longevity biomarker is weak. Extreme TSH values (hypo- or hyperthyroidism) are clearly linked to increased mortality, but the benefit of TSH screening in asymptomatic healthy individuals is debated. The Men’s Wellness Check by MyBody-X includes TSH as one of several markers – this is reasonable within a comprehensive analysis, but isolated TSH measurement is insufficient to make claims about longevity. Important: TSH alone can be misleading; for a full thyroid assessment, free T3 and T4 are needed. Evidence: human-moderate (epidemiological studies, but no randomized longevity trials). Caveat: consumer tests without clinical interpretation may lead to false conclusions.
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