Evidence check: CRP Entzündung in the context of skin aging
T
TIKKI knowledge answer
CRP (C-reactive protein) is a non-specific inflammatory marker produced in the liver. Chronically elevated CRP levels (≥2 mg/L) are linked to low-grade systemic inflammation, a process known as 'inflammaging' that may accelerate skin aging by promoting collagen degradation, loss of elasticity, and barrier dysfunction. However, the evidence for a direct causal role of CRP in skin aging is moderate: observational studies show associations, but confounders like UV exposure, smoking, diet, and genetics are major drivers. A blood CRP test (e.g., high-sensitivity CRP) can indicate general inflammation but cannot specifically diagnose skin aging. MyBody-X tests provide screening-level results that require medical follow-up. Elevated CRP warrants clinical evaluation (e.g., infection, autoimmune disease). For skin aging, lifestyle factors (sun protection, antioxidants, sleep) are more impactful than a single biomarker. Evidence: human-moderate.
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