AMH (Anti-Müllerian Hormone) is produced by granulosa cells of ovarian follicles and is widely used as a marker of ovarian reserve. Lower AMH levels indicate a reduced number of remaining eggs, which is associated with diminished fertility potential. However, AMH does not reflect egg quality or the likelihood of natural conception – it is a quantitative rather than qualitative measure. In reproductive medicine, AMH helps predict response to ovarian stimulation. The evidence is strong (numerous clinical studies), but its predictive value for natural fertility is limited. A normal AMH does not guarantee fertility, and a low level does not mean infertility is certain. Other factors like age, cycle regularity, and partner fertility are equally important. Testing is typically done on day 3 of the menstrual cycle. Reference ranges vary by lab and age, so clinical interpretation is essential.
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