NutriCare | INFINITY DNA-Test: what does this mean exactly?

The NutriCare and INFINITY DNA-Tests by MyBody-X are direct-to-consumer genetic tests that analyze DNA variants related to nutrition, metabolism, and other health areas. The NutriCare test specifically claims to help choose between low-carb and low-fat diets. However, large randomized controlled trials (e.g., DIETFITS, POUNDS LOST) show no clinically useful gene-diet interaction for weight loss. Effect sizes are small and ancestry-dependent. The INFINITY test likely covers a broader panel, including markers like APOA5 (triglycerides) or NR3C1 (stress response). Many associations are mechanistic or based on observational studies, not clinical endpoints. These tests provide interesting insights but are not diagnostic and should not be used to prescribe specific diets or treatments. Evidence: mixed – strong evidence against utility for diet decisions, weak to moderate for individual markers. Sources: no PMIDs provided in context.